Journal of Biomedicine and Biochemistry (JBB) is a medium for global academics to exchange and disseminate their knowledge and the latest discoveries and advances. Journal of Biomedicine and Biochemistry (JBB) follows a libre open access policy under the Creative Commons Attribution 4.0 International public license. The journal publishes four issues annually and All manuscripts undergo rigorous double-blind peer review to ensure scientific quality and acceptance.

Vol. 4 No. 2 (2025)

Number of pages 1-149, List of authors by countries (Iraq, UK, Malaysia, Australia and Jordan)

Published: June 30, 2025

Analysis of the Relationship between NLRP3, Ferritin, MDA, and Catalase Enzyme in Patients with Beta-Thalassemia Major: A Clinical Study

Ali Abd Al-Bari Al-Dhalimi (1), Zainab N. Al-Abady (2)
(1) Directorate of Education in Najaf Governorate, Najaf, Iraq. ,
(2) Department of Chemistry, Faculty of Sciences, University of Al-Qadisiyah, Al-Qadisiyah, Iraq.
1-20
200

Identification and Characterization of Antibiotic-Resistant Bacterial Strains in Hospital Wastewater

Yasmeen Ali Hussein (1), Widad Abd AL Jabbar (2), Hayder Al-Aubaidy (3)
(1) Department of Pharmacology, College of Pharmacy, University of Alkafeel, Najaf 54001, Iraq. ,
(2) Department of Pharmacology, College of Pharmacy, Al-Mustaqbal University, Hillah, Babylon 51001, Iraq. ,
(3) Department of Biochemistry, New Medical Education Australia, Brisbane, QLD 4000, Australia.
21-41
72

Impacts of Drug Abuse and Addiction and Effects of Pharmaceuticals Misuse: Review Article

Hiba Hussein Fadil Mahdi (1), Ghassan Jasim Mohammed (2)
(1) Faculty of Nursing, University of Babylon, Babylon, 51002, Iraq. ,
(2) Faculty of Pharmacy, University of Babylon, Babylon,51002, Iraq.
42-56
102

Development of 3D Bioprinted Vascularized Cardiac Tissues Using Patient-Derived Stem Cells: A Preclinical Study

Mohammed R. Abd Ali (1), Mohammed Malih Radhi (2), Hussein Assak Al-Hachami (3), Nada Nada Khazal K. Hindi (4), Rusull Hamza K. AL-Jubori (5), Wamidh H. Talib (6)
(1) Department of Basic and Medical Science, College of Nursing, University of Babylon, Hillah, 51001, Iraq. ,
(2) Community Health Nursing, College of Health and Medical Techniques, Al-Furat Al-Awsat Technical University, AlNajaf , 54001, Iraq. ,
(3) Specialist Physician in Community Medicine, Al-Baladiyat Sector One, Baghdad Al-Rusafa Health Directorate, Ministry of Health, Baghdad, Iraq. ,
(4) Department of Basic and Medical Science, College of Nursing, Babylon University, Pharmacy College, Al-Mustaqbal University, Hillah, 51001, Iraq. ,
(5) Babylon Health Directorate, Hillah, 51001, Iraq. ,
(6) Faculty of Allied Medical Sciences, Applied Science Private University, Amman 11931, Jordan.
57-74
94

Recent Progress in Targeted Drug Delivery Systems for Cancer Treatment

Ghadah Ali Al-Oudah (1), Noor Thamer Mahmood (2), Dhelal Fouad Mohammed (3)
(1) College of Pharmacy, Al-Mustaqbal University, Babylon, Hillah, 51001, Iraq ,
(2) Computer Science, University of Babylon , Hillah, 51001, Iraq. ,
(3) University of Central Lancashire (UCLan), Preston, UKOSPAP student at Aston University, Birmingham, UK.
75-97
63

Mechanisms of Heavy Metal Toxicity at the Cellular, Molecular and General Health Levels

Ameera Jasim Al-Aaraji Oudah (1), Ruwaida Wahab Salman AL-Jebory (2), Ahmed Hasan R. Al.Zurfi (3), Haider Mahmod Jasim (4)
(1) Department of Clinical Chemistry, Hammurabi College of Medicine, University of Babylon, Hillah 51001, Babylon, Iraq. ,
(2) Department of Clinical Chemistry, Hammurabi College of Medicine, University of Babylon, Hillah 51001, Babylon, Iraq. ,
(3) Department of Internal Medicine, Hammurabi College of Medicine, University of Babylon, Hillah 51001, Iraq. ,
(4) School of Biological Sciences, Universitiy Sains Malaysia, Gelugor, Penang, Malaysia.
98-123
74

Checkpoint Inhibitors in Cancer Immunotherapy: Mechanisms of Action and Resistance

Ghadah Ali Al-Oudah (1), Wallaa Luay Alfalluji (2), Ahmed M N Al-Ajrash (3)
(1) Department of Internal Medicine, Hammurabi College of Medicine, University of Babylon, Hillah 51001, Iraq. ,
(2) Hammurabi Medical College, University of Babylon, Babil, Iraq. ,
(3) Respiratory Department, Blackpool Teaching Hospitals NHS Foundation Trust, Blackpool, UK.
124-149
70
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